📋 Analysis Log
Error Information
📁 Main Task Files (for subsequent analysis) （Inherited from parent）
📊 Task Summary
Result Files
Tool Introduction & Use Cases
Gene-Drug Sensitivity Correlation is primarily used for calculating and visualizing correlations (between samples or genes).
Predict sensitivity (IC50 values) of TCGA samples to hundreds of anti-cancer drugs using pRRophetic algorithm, and analyze the correlation between target gene expression levels and drug sensitivity. This tool helps identify drugs potentially regulated by specific gene expression, providing references for precision medicine and personalized medication. The tool automatically screens drugs significantly correlated with the target gene and generates correlation scatter plots.
Main Use Cases:
- Explore data patterns and support subsequent in-depth analysis
Key Features:
- Standardized processing and result export
- Key charts and table output
- Can be used as input for subsequent analysis
Parameter Details
| Parameter | Meaning & Recommendations | Settings |
|---|---|---|
| Expression Matrix File | TCGA格式的RNA-seq counts表达矩阵 | Required Default: None |
| Target Gene | 要分析的目标基因名称（Gene Symbol） | Required Default: TP53 |
| Correlation Coefficient Threshold | 筛选药物的相关系数绝对值阈值 | Required Default: 0.3 |
| P-value Threshold | 筛选药物的P值阈值 | Required Default: 0.05 |
Input File Requirements
Please ensure your input file format is correct, as this is fundamental to successful analysis. Typically, you need to provide a data matrix containing gene/protein expression values.
This tool does not currently provide sample files. Please refer to the common format: typically CSV or TXT files with the first column as gene/protein IDs, followed by expression values for each sample.
Frequently Asked Questions
Q: How long does the analysis take?
A: Estimated execution time is approximately 1200 seconds, depending on your data size and current server load.
Q: What if the analysis fails?
A: If the analysis fails, your credits will not be deducted. First, check if your input file format matches the sample file, or adjust parameters based on error messages. If the problem persists, please contact us through the page's feedback function.
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